Computational and Developmental Psychiatry Lab

Stegmann, Y., Reutter, M., Hutterer, K., Hildebrandt, L., Deckert, J., Deserno, L., ..., & Gamer, M. (2024). How to measure fear generalization? Reliability and validity of commonly used indices [Preprint]. OSF Preprints. https://doi.org/10.31234/osf.io/fk26y

Zech, H., Waltmann, M., Lee, Y., Reichert, M., Bedder, R. L., Rutledge, R., ..., Deserno, L., & the ReCoDe Consortium (2023). Gamified smartphone experiments reveal that fluctuations in decision-making precede changes in real-life drinking in alcohol use disorder [Preprint]. OSF Preprints. https://doi.org/10.17605/OSF.IO/9ZE2U

Hachenberger, J., Mayer, A., Kerkhoff, D., Eyssel, F., Fries, S., Lonsdorf, T. B., ..., Deserno, L., Lemola, S. (2023). Reliability, occasion specificity, and validity of the Stroop and Go/No-Go tasks in the ecological momentary assessment context. [Preprint].

Bohmeier, B., Cybinski, L. M., Gromer, D., Bellinger, D., Deckert, J., ..., Deserno, L., ..., Herrmann, M. J. (2025). Intermittent theta burst stimulation of the left dorsolateral prefrontal cortex has no additional effect on the efficacy of virtual reality exposure therapy for acrophobia. Behavioural Brain Research, 476, 115232.

Liu, S., Haucke, M., Groß, R., Schneider, K., Shin, J., Arntz, F., Bach, P., ..., Deserno, L., ..., Zech, H., ..., Reichert, M. (2025). Real-time mechanism-based interventions for daily alcohol challenges: Protocol for ecological momentary assessment and intervention. Digital Health, 11, 20552076241311731.

Waltmann, M., Herzog, N., Reiter, A. M., Villringer, A., Horstmann, A., & Deserno, L. (2024). Neurocomputational mechanisms underlying differential reinforcement learning from wins and losses in obesity with and without binge eating. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9(12), 1281–1290.

Scholz, V., Waltmann, M., Herzog, N., Horstmann, A., & Deserno, L. (2024). Decrease in decision noise from adolescence into adulthood mediates an increase in more sophisticated choice behaviors and performance gain. PLoS Biology, 22(11), e3002877.

Hein, G., Huestegge, L., Böckler-Raettig, A., Deserno, L., Eder, A. B., Hewig, J., ... (2024). A social information processing perspective on social connectedness. Neuroscience & Biobehavioral Reviews, 105945.

Meisenzahl, E., Schultze-Lutter, F., Stegmüller, V., Schulte-Körne, G., ..., Deserno, L., ..., Wege, N. (2024). Stressors during the prodromal phase of major depressive episode (CHR-D). Frontiers in Psychiatry, 15, 1389370.

Weiß, M., Gutzeit, J., Pryss, R., Romanos, M., Deserno, L., & Hein, G. (2024). Common and differential variables of anxiety and depression in adolescence: a nation-wide smartphone-based survey. Child and Adolescent Psychiatry and Mental Health, 18(1), 103.

Spanagel, R., Bach, P., Banaschewski, T., Beck, A., Bermpohl, F., Bernardi, R. E., ..., Deserno, L., ..., Other members of the ReCoDe Consortium (2024). The ReCoDe addiction research consortium: Losing and regaining control over drug intake—Findings and future perspectives. Addiction Biology, 29(7), e13419.

Hoffmann, S., Gerhardt, S., Mühle, C., Reinhard, I., Reichert, D., Bach, P., ..., Deserno, L., ..., ReCoDe Consortium (2024). Associations of menstrual cycle and progesterone-to-estradiol ratio with alcohol consumption in alcohol use disorder: a sex-separated multicenter longitudinal study. American Journal of Psychiatry, 181(5), 445–456.

Meisenzahl, E., Wege, N., Stegmüller, V., Schulte-Körne, G., Greimel, E., ..., Deserno, L., ..., Schultze-Lutter, F. (2024). Clinical high risk state of major depressive episodes: Assessment of prodromal phase, its occurrence, duration and symptom patterns by the instrument the DEpression Early ... Journal of Affective Disorders, 351, 403–413.

Herzog, N., Hartmann, H., Janssen, L. K., Waltmann, M., Fallon, S. J., Deserno, L., Horstmann, A. (2024). Working memory gating in obesity: Insights from a case-control fMRI study. Appetite, 195, 107179.

Gregorová, K., Eldar, E., Deserno, L., & Reiter, A. M. F. (2024). A cognitive-computational account of mood swings in adolescence. Trends in Cognitive Sciences, 28(4), 290–303. https://doi.org/10.1016/j.tics.2024.01.006

Herzog, N., Hartmann, H., Janssen, L. K., Kanyamibwa, A., Waltmann, M., ..., Deserno, L., ..., Horstmann, A. (2024). Working memory gating in obesity is moderated by striatal dopaminergic gene variants. Elife, 13, RP93369.

Aster, H. C., Waltmann, M., Busch, A., Romanos, M., Gamer, M., van Noort, B. M., ..., Deserno, L. (2024). Impaired flexible reward learning in ADHD patients is associated with blunted reinforcement sensitivity and neural signals in ventral striatum and parietal cortex. NeuroImage: Clinical, 42, 103588.

Zech, H., Waltmann, M., Lee, Y., Reichert, M., Bedder, R. L., Rutledge, R. B., ... Deserno, L., & the ReCoDe-Consortium (2023). Measuring self-regulation in everyday life: Reliability and validity of smartphone-based experiments in alcohol use disorder. Behavior Research Methods, 55(8), 4329–4342.

Chetitah, M., Müller, J., Deserno, L., Waltmann, M., & von Mammen, S. (2023). Gamification framework for reinforcement learning-based neuropsychology experiments. In Proceedings of the 18th FDG, 1–4.

Scholz, V., Waltmann, M., Herzog, N., Reiter, A., Horstmann, A., & Deserno, L. (2023). Cortical grey matter mediates increases in model-based control and learning from positive feedback from adolescence to adulthood. Journal of Neuroscience, 43(12), 2178–2189.

Waltmann, M., Herzog, N., Reiter, A. M. F., Villringer, A., Horstmann, A., & Deserno, L. (2023). Diminished reinforcement sensitivity in adolescence is associated with enhanced response switching and reduced coding of choice probability in the medial frontal pole. Developmental Cognitive Neuroscience, 101226.

Geißler, J., Deserno, L., Romanos, M., Spiegler, J., & Jans, T. (2023). 9/m mit Konzentrationsstörungen. Monatsschrift Kinderheilkunde, 171 (Suppl 2), 121–125.

Fromm, S., Katthagen, T., Deserno, L., Heinz, A., Kaminski, J., & Schlagenhauf, F. (2023). Belief updating in subclinical and clinical delusions. Schizophrenia Bulletin Open, 4(1), sgac074.

Waltmann, M., Schlagenhauf, F., & Deserno, L. (2022). Sufficient reliability of the behavioral and computational readouts of a probabilistic reversal learning task. Behavior Research Methods, 54(6), 2993–3014.

Lim, S. J., Thiel, C., Sehm, B., Deserno, L., Lepsien, J., & Obleser, J. (2022). Distributed networks for auditory memory differentially contribute to recall precision. NeuroImage, 256, 119227.

Deeken, F., Reichert, M., Zech, H., Wenzel, J., Wedemeyer, F., Aguilera, A., ..., Deserno, L., ..., and the ReCoDe Consortium (2022). Patterns of alcohol consumption among individuals with alcohol use disorder during the COVID-19 pandemic and lockdowns in Germany. JAMA Network Open, 5(8), e2224641–e2224641.

Schulz, C. C., von Klitzing, K., Deserno, L., Sheridan, M. A., Crowley, M. J., ..., White, L. O. (2022). Emotional maltreatment and neglect impact neural activation upon exclusion in early and mid-adolescence: An event-related fMRI study. Development and Psychopathology, 34(2), 573–585.

Aster, H. C., Romanos, M., Walitza, S., Gerlach, M., Mühlberger, A., Rizzo, A., ..., Deserno, L. (2022). Responsivity of the striatal dopamine system to methylphenidate. Frontiers in Psychiatry, 13, 804730.

Zech, H. G., Reichert, M., Ebner-Priemer, U. W., Tost, H., Rapp, M. A., Heinz, A., Dolan, R. J., Smolka, M. N., Deserno, L. (2022). Mobile data collection of cognitive-behavioral tasks in substance use disorders: where are we now? Neuropsychobiology, 81(5), 438–450.

Sebold, M., Kiebel, S. J., Smolka, M. N., Heinz, A., & Deserno, L. (2022). Computational theories of alcohol use disorder: mapping learning and choice mechanisms on symptoms. Neuropsychobiology, 81(5), 339–356.

Panitz, M., Deserno, L., Kaminski, E., Villringer, A., Sehm, B., & Schlagenhauf, F. (2022). Anodal tDCS over the medial prefrontal cortex enhances behavioral adaptation after punishments. Cerebral Cortex Communications, 3(1), tgac006.

Deserno, L., Moran, R., Michely, J., Lee, Y., Dayan, P., & Dolan, R. J. (2021). Dopamine enhances model-free credit assignment through boosting of retrospective model-based inference. eLife, 10, e67778. https://doi.org/10.7554/eLife.67778

Waltmann, M., Herzog, N., Horstmann, A., & Deserno, L. (2021). Loss of control over eating: A systematic review of task based research into impulsive and compulsive processes in binge eating. Neuroscience & Biobehavioral Reviews, 129, 330–350. https://doi.org/10.1016/j.neubiorev.2021.07.016

Beierle, F., Schobel, J., Vogel, C., Allgaier, J., Mulansky, L., Haug, F., Haug, J., ..., Deserno, L., ..., Pryss, R. (2021). Corona health—A study-and sensor-based mobile app platform exploring aspects of the COVID-19 pandemic. International Journal of Environmental Research and Public Health, 18(14), 7395.

Nees, F., Deserno, L., Holz, N. E., Romanos, M., & Banaschewski, T. (2021). Prediction along a developmental perspective in psychiatry: how far might we go? Frontiers in Systems Neuroscience, 15, 670404.

Janssen, L. K., Mahner, F. P., Schlagenhauf, F., Deserno, L., & Horstmann, A. (2020). Reliance on model-based and model-free control in obesity. Scientific Reports, 10(1), 22433.

Deserno, L., & Hauser, T. U. (2020). Beyond a cognitive dichotomy: Can multiple decision systems prove useful to distinguish compulsive and impulsive symptom dimensions? Biological Psychiatry, 88(10), e49–e51.

Heinz, A., Kiefer, F., Smolka, M. N., Endrass, T., Beste, C., Beck, A., Liu, S., ..., Deserno, L., ..., Spanagel, R. (2020). Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe). Addiction Biology, 25(2), e12866.

Schad, D. J., Rapp, M. A., Garbusow, M., Nebe, S., Sebold, M., Obst, E., Sommer, C., Deserno, L., ..., Huys, Q. J. M. (2020). Dissociating neural learning signals in human sign-and goal-trackers. Nature Human Behaviour, 4(2), 201–214.

Deserno, L., Boehme, R., Mathys, C., Katthagen, T., Kaminski, J., Stephan, K. E., Heinz, A., Schlagenhauf, F. (2020). Volatility estimates increase choice switching and relate to prefrontal activity in schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5(2), 173–183.